Analytical Chemistry

SGS quality control labs have extensive capabilities in analytical chemistry. We perform testing in strict accordance with USP, BP, EP, JP, ACS and other procedures, using both sophisticated analytical instrumentation as well as traditional wet chemistry techniques. In addition to the tests found on our website, we perform many more tests not listed. Please contact us by completing the Request for Information or Request for Quotation on your chemistry testing requirements found under Related Links section of this page.

• Methods Development and Validation
• Methods Transfer
• Pharmaceutical Stability Studies
• Photostability Storage -ICH Option 2
• Environmental Chamber Storage of Stability Study Samples

SGS maintains several environmental chambers at the temperature and humidity conditions commonly used for pharmaceutical stability studies: 25ºC with 60% R.H., 30ºC with 60% R.H., and 40ºC with 75% R.H. Alternate conditions are also available. The temperature and humidity in all of our chambers is continuously monitored by our Rees™ Facilities Monitoring System. We will either store samples for stability studies where SGS is performing the testing or we will rent space to clients who do their testing in-house. Stability study samples will be removed from the environmental chamber and shipped back at client specified intervals. Laboratory reports documenting the storage conditions will be sent with each group of returned samples. Fees are primarily based on the volume of space required. Inquiry on these fees can be done by filling out our Request for Quotation located on the right side of the page.

• Infrared Spectroscopy (FTIR)
• UV and/or Visible Spectrum
• Gas Chromatography
• Liquid Chromatography
• Ion Chromatography

SGS has extensive GC and LC capabilities. Gas chromatography detectors available for testing are flame ionization (FID) and thermal conductivity (TCD). We also has headspace autosamplers and a gas sampling valve. Liquid chromatography capabilities include refractive index (RI), photodiode array (PDA), electrochemical (ECD) and ultraviolet (UV) detectors. Ion chromatography using a conductivity detector is also available. We have experienced chromatographers who specialize in the development and validation of test methods. SGS uses the Agilent Chemstore chromatography data management system. This system has been fully validated to meet 21 CFR Part 11 electronic signature regulations.

Quantitation of Individual Metals by Atomic Absorption

• Aluminum
• Cadmium
• Calcium
• Chromium
• Cobalt
• Copper
• Iron
• Lead
• Magnesium
• Manganese
• Molybdenum
• Nickel
• Palladium
• Potassium
• Silicon
• Silver
• Sodium
• Zinc

Sample Preparation

Ashing, extraction or other sample preparation is required for solid materials. Several elements can be analyzed from one sample preparation.

Please contact our Analytical Chemistry Specialists for a quotation on your chemistry testing requirements or fill out our online Request for Quotation form.